PCOS Fertility Treatment in Singapore

Helping women with PCOS achieve healthy pregnancies

Polycystic Ovary Syndrome (PCOS) is a leading cause of infertility. With early diagnosis and a personalised treatment plan that may include lifestyle changes, medications, and reproductive technologies, many women with PCOS go on to conceive successfully.

This article covers how PCOS affects fertility and how a personalised treatment plan can improve your chances of conception.

What is PCOS and How Does It Affect Fertility?

PCOS is a medical condition which is characterised by hormonal imbalance, elevated androgens and insulin resistance, which disrupts follicle maturation and ovulation. This leads to fewer ovulations, irregular menstrual cycles (often exceeding 35 days), reduced egg quality, and potentially reduced pregnancy rates and higher miscarriage risks.

Ovulatory Dysfunction

Menstrual cycles longer than 35 days apart or having fewer than eight menstrual bleeds a year.

Polycystic ovaries on transvaginal ultrasound

Presence of 20 or more follicles in at least one ovary or an ovarian volume greater than 10 cm³.

Clinical or Biochemical hyperandrogenism

Presence of excessive acne or facial/body hair growth or elevated male hormones found in laboratory tests.

The diagnostic process will include taking a comprehensive menstrual history, physical assessment for signs of hyperandrogenism, undergoing hormone and metabolic blood tests, and a transvaginal ultrasound.

Recognising and Diagnosing PCOS

PCOS is diagnosed using the modified Rotterdam criteria, which requires the presence of two of three key features after other causes have been excluded. The key features are:

PCOS Treatment Options in Singapore

Lifestyle Modifications – The Essential First Step

A structured program combining a lower glycaemic balanced diet, regular physical activity (at least 150 minutes/week), stress management, and good sleep can significantly improve insulin sensitivity, regulate menstrual cycles, and optimise fertility. Even a modest 5 to10% weight loss can restore ovulation and boost fertility outcomes.

Medications to Promote Ovulation & Hormone Balance

Second-Line Treatments

Assisted Reproductive Technologies (ART)

Supportive Therapies & Long‑Term Health

When to Consult a PCOS or Fertility Specialist in Singapore?

Early engagement with a fertility specialist can reduce delays and improve reproductive outcomes.

You can expect the following treatment pathway:​

Assessment

Review medical & menstrual history, perform ultrasound and blood tests.

Lifestyle First

Focus on weight management, diet, exercise, sleep, and stress control.

Medication to Induce Ovulation

Start with Letrozole ± Metformin ± Myoinositol.

Second-Line

If necessary, proceed to gonadotropins, ovarian drilling, or IUI.

Advanced Options

IVF with safe protocols for management of OHSS risk, or other ART if needed.

Holistic Care

Include supplements, skin care, psychological support, and metabolic surveillance.

Choosing the Right Clinic in Singapore

At Daniel Koh Clinic, we offer:

Dr Daniel Koh

About Our Specialist

Obstetrician & Gynaecologist Singapore

BMBS (AUS), M.MED (O&G, SG), FRCOG (UK), FAMS (SG)

Dr Daniel Koh is a highly respected obstetrician and gynaecologist based at Gleneagles Medical Centre, with extensive experience in both medical and surgical termination of pregnancy (TOP) in Singapore.

He is a Ministry of Health-accredited abortion provider and counsellor, known for his commitment to evidence-based care, patient autonomy, and confidentiality. Dr Koh provides clear, non-judgmental guidance to individuals navigating unplanned pregnancies, ensuring that every patient is fully informed and supported throughout the process.

How WE Can Help

Our Services

Providing a comprehensive suite of services to prioritise your needs and comfort at every step of the way in your fertility journey.

Obstetrics

Antenatal care & delivery, maternal & fetal medicine including high-risk pregnancies and fetal screening

Gynaecology

Abortion, family planning, abnormal Pap smears, fibroid and ovarian cyst management

Fertility

Fertility ScreeningIUIIVFEgg Freezing, Pregnancy Confirmation

Menstrual Problems

Frequently Asked Questions

Below you will find answers to common questions about abortion in Singapore.

Can PCOS cause infertility?

Yes. Polycystic ovary syndrome (PCOS) can affect both ovulation and egg quality, making it more difficult for some women to conceive.

In a normal cycle, a mid-cycle surge in luteinising hormone (LH) triggers the release of an egg. In women with PCOS, LH levels tend to remain mildly elevated throughout the cycle. This prevents the normal surge, leaving eggs trapped within their follicles instead of being released for fertilisation.

Yes. High insulin levels and excess male hormones (androgens) in PCOS can slow egg maturation. Even if ovulation occurs, the eggs may be less likely to fertilise successfully or develop into a healthy embryo.

Yes, family history increases the likelihood of PCOS, though it is also influenced by lifestyle and environmental factors.

Not necessarily. PCOS diagnosis requires at least two of the three Rotterdam criteria (infrequent menstrual cycles, clinical signs of hyperandrogenism and polycystic ovaries).

  • IUI (public): Starts from SGD 660 per cycle (before GST) and usually excludes consultation fees, medications or diagnostic tests.
  • IUI (private): Starts from $2000 (before GST) per cycle and usually includes consultation fees, medications and ultrasound scans.
  • IVF (public): Starts from SGD12,000 (before GST) per cycle
  • IVF (private): Starts from SGD20,000 (before GST) per cycle.
  • Medication costs vary by protocol and dosage, ranging from approximately S$2,000 to S$6,000 per cycle.

Take Charge of Your Fertility Journey

Polycystic ovary syndrome (PCOS) is both common and manageable. With timely diagnosis and a personalised treatment plan, you can rebalance your hormones, restore ovulation, and enhance fertility outcomes.

Choosing the Right Care: Daniel Koh Clinic for Women and Fertility Services in Singapore

At Daniel Koh Clinic, you will benefit from continuity of care under Dr Daniel Koh, a MOH-accredited fertility specialist who is experienced in both reproductive medicine and maternal‑fetal medicine. He offers comprehensive support from your initial fertility consultation through to the delivery of your child.

Book a consultation with Dr Daniel to discuss your fertility options and receive a personalised care plan.

Get In Touch

We're here to help.

Our friendly team is looking forward to serving you. For urgent enquiries and appointment requests, please call or WhatsApp us directly.